Research Information System
Turkiye Klinikleri Journal of Medical Sciences, vol.30, no.3, pp.1061-1066, 2010 (SCI-Expanded)
Objective: Because the etiology and pathophysiology of the functional dyspepsia remains unclear, the optimal management is still controversial. This study was aimed to determine the actual gastric wall thicknesses in the subgroups of functional dyspepsia patients, and to investigate whether there was any correlation with the symptoms. Material and Methods: Functional dyspepsia patients (n= 136) were divided into six groups in regard to the predominant symptom; as group 2: epigastric discomfort; group 3: epigastric pain; group 4: nausea; group 5: vomiting; group 6: bloating and group 7: early satiety. Control group was selected from the patients who underwent ultrasonographic examination for gynecologic or urinary reasons and had no gastrointestinal symptoms (group 1). The patients were investigated by hydrogastric sonography following conventional transabdominal sonography. Same independent radiologist blind to the symptoms, measured the thicknesses of anterior and posterior gastric walls in fundus, corpus and antrum. Results: Anterior and posterior fundus walls were detected as significantly thickened in groups 2 and 7 (p< 0.05). Both the anterior and the posterior walls of the corpus and antrum were found significantly thicker than the other groups in the group 3 (p< 0.05). Conclusion: This study documented significant gastric wall thickness differences between the subgroups of the functional dyspepsia patients. © 2010 by Türkiye Klinikleri.