Biological activities of some natural compounds from Sideritis sipylea boiss

Logoglu E., Arslan S., Oktemer A., Sakiyan I.

PHYTOTHERAPY RESEARCH, vol.20, no.4, pp.294-297, 2006 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 20 Issue: 4
  • Publication Date: 2006
  • Doi Number: 10.1002/ptr.1855
  • Journal Name: PHYTOTHERAPY RESEARCH
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.294-297
  • Keywords: Sideritis siplylea Boiss, antimicrobial activity, siderol, linearol, epicandicandiol, TERPENIC COMPONENTS, SPANISH LABIATAE, MICROBIOLOGICAL TRANSFORMATION, DITERPENES
  • Ankara University Affiliated: No

Abstract

In this work, several diterpenes including siderol, linearol and epicandicandiol were isolated from Sideritis sipylea Boiss collected from Izmir-Karaburun-Akdag, Turkey. In addition, diacetate derivatives of linearol and epicandicandiol were obtained. The antimicrobial activites of all these compounds against the bacteria Staphylococcus aureus (ATTC 25923), Bacillus subtilis (ATCC 6633), Escherichia coli (ATCC 11230), Pseudomonas aeruginosa (ATCC 27853) and the fungus Candida albicans (ATCC 90028) were studied. Antimicrobal activity was measured by the well-diffusion method. Except for C. albicans all microorganisms were tested against antibiotic discs in comparison with the studied compounds. Copyright (c) 2006 John Wiley & Sons, Ltd.