Akademik Veri Yönetim Sistemi
CURRENT EYE RESEARCH, cilt.46, sa.5, ss.731-738, 2021 (SCI-Expanded)
Purpose To evaluate the efficacy of visual rehabilitation with microperimeter biofeedback in patients with central scotoma. Materials and Methods 35 consecutive patients with central scotoma (17 age-related macular degeneration (AMD), 14 Stargardt disease, and 4 cone dystrophy) were included in the study. Visual acuity, reading performance by Minnesota Low Vision Reading Test (MNREAD), quality of life by 25-item National Eye Institute Visual Function Questionnaire (NEI VFQ-25), and fixation analysis by MAIA microperimeter were evaluated before and 1 month after training. The rehabilitation program consisted of 10 training sessions of 10 minutes. Results The median best-corrected visual acuity (BCVA) was 0.80 logMAR (range 0.3 to 1.3 logMAR). Fifty-nine percent of patients with AMD developed a preferred retinal locus (PRL) nasal to the fovea, and 64% of the patients with Stargardt disease preferred a PRL superior to the fovea. The PRL location in 3 of 4 cone dystrophy patients was nasal to the fovea. The mean PRL distance from the fovea was 7.57 +/- 3.61 degrees. Fixation stability improved with P1 values of 22.34 +/- 11.81 versus 32.05 +/- 18.79 (p= .003) and 95% bivariate contour ellipse area (BCEA) values of 41.6 versus 23.6 (p= .018) before and after training, respectively. There was a significant difference in reading acuity between before and after training (p= 0.008). The overall score and near activities score of NEI VFQ-25 were found to be increased at the end of the rehabilitation (p< 0.001). Conclusion Rehabilitation with acoustic biofeedback in patients with central scotoma looks like a useful technique for improving fixation stability, reading performance and quality of life.