Ocular Inflammatory Events Following COVID-19 Vaccination in the Paediatric Population: A Multinational Case Series

Testi I., Brandao-de-Resende C., De-La-Torre A., Concha-Del-Rio L. E., Cheja-Kalb R., Mahendradas P., ...Daha Fazla

OCULAR IMMUNOLOGY AND INFLAMMATION, cilt.32, sa.7, ss.1237-1242, 2024 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 32 Sayı: 7
  • Basım Tarihi: 2024
  • Doi Numarası: 10.1080/09273948.2023.2220782
  • Dergi Adı: OCULAR IMMUNOLOGY AND INFLAMMATION
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CAB Abstracts, CINAHL, EMBASE, MEDLINE, Veterinary Science Database
  • Sayfa Sayıları: ss.1237-1242
  • Anahtar Kelimeler: COVID-19, ocular inflammation, paediatric, uveitis, vaccination, MULTIFOCAL CHOROIDITIS
  • Ankara Üniversitesi Adresli: Evet

Özet

BackgroundOcular inflammatory events following COVID-19 vaccination have been reported in the adult population.MethodsMultinational case series of patients under the age of 18 diagnosed with ocular inflammatory events within 28 days of COVID-19 vaccination.ResultsTwenty individuals were included. The most common event was anterior uveitis (n = 8, 40.0%), followed by intermediate uveitis (7 patients, 35%), panuveitis (4 patients, 20%), and posterior uveitis (1 patient, 5%). The event was noticed in the first week after vaccination in 11 patients (55.0%). Twelve patients (60.0%) had a previous history of intraocular inflammatory event. Patients were managed with topical corticosteroids (n = 19, 95.0%), oral corticosteroids (n = 10, 50.0%), or increased dose of immunosuppressive treatment (n = 6, 30.0%). Thirteen patients (65.0%) had a complete resolution of the ocular event without complications. All patients had a final visual acuity unaffected or less than three lines of loss.ConclusionOcular inflammatory events may happen in the paediatric population following COVID-19 vaccination. Most events were successfully treated, and all showed a good visual outcome.