Aggressive Behavior and Characteristics in Congenital Adrenal Hyperplasia
Handbook of the Behavior and Psychology of Disease, Springer International Publishing Ag, ss.905-920, 2025
- Yayın Türü: Kitapta Bölüm / Araştırma Kitabı
- Basım Tarihi: 2025
- Doi Numarası: 10.1007/978-3-031-73363-5_146
- Yayınevi: Springer International Publishing Ag
- Sayfa Sayıları: ss.905-920
- Anahtar Kelimeler: Aggression, Androgen excess, Behavioral patterns, Congenital adrenal hyperplasia, Hormonal influence, Virilization
- Ankara Üniversitesi Adresli: Evet
Özet
Congenital adrenal hyperplasia (CAH) is an autosomal recessive disorder. Most common types, such as 21-hydroxylase and 11-beta-hydroxylase deficiency, lead to an increase in androgen synthesis. Elevated androgens contribute to the clinical manifestations of the disease. The antenatal and neonatal periods are critical for brain development, and exposure to testosterone during this time can influence various aspects, from gender differentiation to behavioral patterns. CAH is an essential disease for demonstrating the effects of hormones on human behavior. Individuals with CAH have reported impairments in different psychiatric disorders. It is well established that increased androgens during the antenatal period lead to virilization in the brain, shaping lifelong gender-related behaviors. The present chapter aims to provide a current summary of aggressive behavior and characteristics in individuals with CAH.