Ultrasound-Assisted One‐Pot Synthesis of 9-(Substituted heteroaryl) acridinedione Derivatives
Düzce Üniversitesi Bilim ve Teknoloji Dergisi, cilt.9, ss.1610-1620, 2021 (TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 9
- Basım Tarihi: 2021
- Doi Numarası: 10.29130/dubited.926881
- Dergi Adı: Düzce Üniversitesi Bilim ve Teknoloji Dergisi
- Derginin Tarandığı İndeksler: TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.1610-1620
- Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
- Ankara Üniversitesi Adresli: Evet
Özet
An efficient green approach for the synthesis of 9-heteroaryl-acridine-1,8-dione derivatives (3a-f) was accomplished viareactions of dimedone (1) with various heteroaromatic aldehydes(2a-f) and ammonium acetate through one-pot multicomponent reactions in water under mild conditions using ultrasound irradiation in excellent yields. Of the synthesized compounds, 3d-fwere novel and this process presents the advantages of high yields andeasy work-up procedures. Spectral analyses were accomplished by FTIR, 1H NMR, 13C NMR and LC-MS TOF analyses