RNA interference in plant parasitic nematodes

Karakas M.

AFRICAN JOURNAL OF BIOTECHNOLOGY, cilt.7, sa.15, ss.2530-2534, 2008 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 7 Sayı: 15
  • Basım Tarihi: 2008
  • Dergi Adı: AFRICAN JOURNAL OF BIOTECHNOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.2530-2534
  • Anahtar Kelimeler: RNA interference, RNAi, gene expression, plant parasitic nematodes, DOUBLE-STRANDED-RNA, GENETIC INTERFERENCE, MICRORNA BIOGENESIS, RESISTANCE, SENSE
  • Ankara Üniversitesi Adresli: Evet

Özet

RNA interference (RNAi, also called RNA-mediated interference) is a mechanism for RNA-guided regulation of gene expression in which double-stranded ribonucleic acid inhibits the expression of genes with complementary nucleotide sequences. Conserved in most eukaryotic organisms, the RNAi pathway is thought to have evolved as a form of innate immunity against viruses and also plays a major role in regulating development and genome maintenance. RNAi has recently been demonstrated in plant parasitic nematodes. It is a potentially powerful investigative tool for the genome-wide identification of gene function that should help improve our understanding of plant parasitic nematodes. RNAi should help identify gene and, hence, protein targets for nematode control strategies.