Clinically positive axillary lymphadenopathy may lead to false diagnosis of overstaged breast cancer in patients with sjögren's syndrome: A case report


Cipe G., GENÇ V., GENÇ A., Ozben V., Basceken S., Dusunceli E. B.

Journal of Breast Cancer, vol.14, no.4, pp.337-339, 2011 (SCI-Expanded) identifier

  • Publication Type: Article / Article
  • Volume: 14 Issue: 4
  • Publication Date: 2011
  • Doi Number: 10.4048/jbc.2011.14.4.337
  • Journal Name: Journal of Breast Cancer
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.337-339
  • Keywords: Breast neoplasms, Lymphatic diseases, Overstaging, Sjögren's syndrome
  • Ankara University Affiliated: Yes

Abstract

Sjögren's syndrome (SS) is an autoimmune disease that chronic infammation and lymph node proliferation. Patients with SS carry a greater risk of developing lymphoproliferative malignancy. In addition to other organ cancers, breast cancer may also occur in these patients. Considering these, breast cancer in patients with SS can be misdiagnosed as being in an advanced stage particularly in the presence of axillary lymphadenopathy. Here, we report a rare case of a 45-year-old woman with SS who presented with a breast mass. Radiology showed a 4 cm solid lesion and con-glomerates of axillary lymphadonepathy. A breast biopsy revealed ductal carcinoma in situ. A modifed radical mastectomy was performed; however, no axillary metastases were detected. Clinicians should remain vigilant to the possibility that a false clinical impression of axillary metastasis may occur in such patients with breast cancer. Therefore, axillary node status should be verifed frst.