The Effects of J Modulation on Spin-Echo Acquisition and Calculation of Spin-Spin Relaxation Time (T2) from the J-suppressed Data Set

YAMAN A.

Physiological Chemistry and Physics and Medical NMR, cilt.32, sa.1, ss.75-81, 2000 (Scopus) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 32 Sayı: 1
  • Basım Tarihi: 2000
  • Dergi Adı: Physiological Chemistry and Physics and Medical NMR
  • Derginin Tarandığı İndeksler: Scopus, BIOSIS
  • Sayfa Sayıları: ss.75-81
  • Ankara Üniversitesi Adresli: Evet

Özet

The effects of J modulation on localized 1H NMR spectra were observed on metabolites with both a short T2 relaxation time like glutamate and a comparatively long T2 relaxation time like N-acetyl-L-aspartic acid (NAA). All examinations were performed by either the double spin-echo (PRESS) sequence or J-suppressed PRESS (JPRESS) sequence. Both of the sequences allow spectral editing and relaxation time studies of J coupled spins. Water-suppressed proton spectra were obtained at 1.5 T (GE Signa) from a 6-8 ml volume of interest. T1 and T2 relaxation times of some of the major brain metabolites were obtained by varying the repetition time and echo time of the JPRESS sequence.