Akademik Veri Yönetim Sistemi
Kocatepe Veterinary Journal, cilt.15, sa.1, ss.15-28, 2022 (Hakemli Dergi)
The aim of this study is to reveal histological differences between prenatal and adult liver carbohydrate and fat metabolism in chickens and rats. In this study, 30 Wistar albino rats and 30 Ross breed broiler chickens were used. The rats and chickens were divided into groups of 10. These groups were categorized as adult, 14- and 18-day-old fetus groups. In this study, the fat and carbohydrate metabolisms in rat and chicken liver were studied by histological methods, and changes in adult and fetal periods were evaluated comparatively. In the light microscopic examinations of liver carbohydrate accumulation, hepatic glycogen accumulation was similar in the adult rats and chickens. When the hepatic glycogen amount was compared in the 14-day-old rat and chicken fetuses, while glycogen granules were found in most of the chicken fetal hepatocytes, almost no glycogen granules were found in the rat fetuses. This difference between the animals was found to be statistically significant (p<0.001). It was observed that glycogen accumulation in the 18-day-old rat fetuses was less than that in chicken fetuses. This difference between the animals was found to be statistically significant (p=0.013). Light microscopic examinations of liver lipid accumulation showed that similar ratios of lipid droplets were observed in the hepatocytes of adult rats and chickens. Significantly higher amounts of lipid droplets were detected in the 14- and 18-day-old chicken fetus hepatocytes compared with 14- and 18-day-old rat fetus hepatocytes, which was statistically significant (p<0.001).