Palladium-catalyzed regioselective C2-arylation of 5-aminoindole

TAŞKESENLİGİL Y., Lafzi F., KILIÇ H., SARAÇOĞLU N.

JOURNAL OF HETEROCYCLIC CHEMISTRY, vol.56, no.12, pp.3289-3296, 2019 (SCI-Expanded, Scopus) identifier identifier

  • Publication Type: Article / Article
  • Volume: 56 Issue: 12
  • Publication Date: 2019
  • Doi Number: 10.1002/jhet.3724
  • Journal Name: JOURNAL OF HETEROCYCLIC CHEMISTRY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Index Chemicus (IC), Current Chemical Reactions (CCR)
  • Page Numbers: pp.3289-3296
  • Ankara University Affiliated: No

Abstract

Pd(II)-catalyzed C-H arylations of 5-aminoindole using iodobenzenes as aryl source was studied. Despite pivalamide directing group at 5-position of the indole, the direct C2-arylation of the indole observed in high yields and with high regioselectivity.