Design, Optimization, and Characterization of Lysozyme-Loaded Poly(epsilon-Caprolactone) Microparticles for Pulmonary Delivery

DEVRİM GÖKBERK B., Erdinc N.

JOURNAL OF PHARMACEUTICAL INNOVATION, cilt.18, sa.1, ss.325-338, 2023 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 18 Sayı: 1
  • Basım Tarihi: 2023
  • Doi Numarası: 10.1007/s12247-022-09648-8
  • Dergi Adı: JOURNAL OF PHARMACEUTICAL INNOVATION
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, INSPEC
  • Sayfa Sayıları: ss.325-338
  • Anahtar Kelimeler: Microparticles, Optimization, Lysozyme, Cystic fibrosis, Pulmonary delivery, ANTIMICROBIAL PEPTIDES, IN-VITRO, PROTEIN, MICROSPHERES, DRUG, ACID), ENCAPSULATION, STABILITY, CARRIER
  • Ankara Üniversitesi Adresli: Evet

Özet

Purpose The success of the treatment of lung diseases with minimized side effects depends on the optimum design of micro-particulate systems for pulmonary delivery that provide local delivery of drugs. This study aims to develop and evaluate optimized drug delivery systems against cystic fibrosis for pulmonary delivery.