Circulating adhesion molecule levels in childhood asthma.

DOĞU E. F., Ikinciogullari A., Egin Y., Babacan E.

Indian pediatrics, vol.39, no.11, pp.1017-1021, 2002 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 39 Issue: 11
  • Publication Date: 2002
  • Journal Name: Indian pediatrics
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1017-1021
  • Ankara University Affiliated: Yes

Abstract

The present study aims at comparing the levels of circulating forms of E-selectin, ICAM-1 and VCAM-1 in 10 patients with acute asthma, 10 stable atopic asthmatics, 10 nonatopic stable asthmatics and 10 age-matched healthy children. sE-selectin levels of patients with acute asthma were found to be significantly higher than that of the other three groups. The insignificant rise in sICAM-1 levels was attributed to the usage of inhaler corticosteroids. Serum sE-selectin and sICAM-1 seem to be promising serological markers for monitoring disease activity in childhood asthma.