Scavenging effect and antispasmodic activity of the essential oil of Cyclotrichium niveum

Cetinus S. A., Goze I., Sarac B., VURAL N.

FITOTERAPIA, vol.78, no.2, pp.129-133, 2007 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 78 Issue: 2
  • Publication Date: 2007
  • Doi Number: 10.1016/j.fitote.2006.10.006
  • Journal Name: FITOTERAPIA
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.129-133
  • Keywords: Cyclotrichium niveum, antioxidant activity, antispasmodic activity, ANTIOXIDANT ACTIVITIES, EXTRACTS, LAMIACEAE
  • Ankara University Affiliated: No

Abstract

The radical scavenging and the spasmolitic activity of Cyclotrichium niveum essential oil were evaluated in vitro. It showed an IC50 of 1750 mu g/ml on DPPH method and dose dependently (0.1, 0.5 and 1 mg/ml) inhibits the contraction induced by carbachol on rabbit bladder from 15 to 100%. Moreover, it was able to inhibit the rat ileum muscle by 30 to 100%. (c) 2006 Elsevier B.V All rights reserved.