Therapeutic evaluation of interleukin 1-beta antagonist Anakinra against traumatic brain injury in rats

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Hasturk A. E., Yilmaz E. R., Turkoglu E., Kertmen H., Horasanli B., Hayirli N., ...Daha Fazla

ULUSAL TRAVMA VE ACIL CERRAHI DERGISI-TURKISH JOURNAL OF TRAUMA & EMERGENCY SURGERY, cilt.21, sa.1, ss.1-8, 2015 (SCI-Expanded, Scopus, TRDizin)

• Yayın Türü: Makale / Tam Makale
• Cilt numarası: 21 Sayı: 1
• Basım Tarihi: 2015
• Doi Numarası: 10.5505/tjtes.2015.57894
• Dergi Adı: ULUSAL TRAVMA VE ACIL CERRAHI DERGISI-TURKISH JOURNAL OF TRAUMA & EMERGENCY SURGERY
• Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
• Sayfa Sayıları: ss.1-8
• Anahtar Kelimeler: Antioxidant, anakinra, interleukin-1, neuroprotection, traumatic brain injury, LIPID-PEROXIDATION, NEUROPROTECTION, EXPRESSION, DISEASE
• Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
• Ankara Üniversitesi Adresli: Evet

Özet

BACKGROUND: The aim of this study was to evaluate the therapeutic efficiency of Anakinra, an IL-1 beta antagonist with anti-inflammatory effects, in an experimental model of traumatic brain injury (TBI).