An Insidious Danger in Children With Familial Mediterranean Fever Colchicine Intoxication

VATANSEVER G., Karadeniz C., KENDİRLİ T.

PEDIATRIC EMERGENCY CARE, cilt.31, sa.9, ss.652-653, 2015 (SCI-Expanded, Scopus) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 31 Sayı: 9
  • Basım Tarihi: 2015
  • Doi Numarası: 10.1097/pec.0000000000000545
  • Dergi Adı: PEDIATRIC EMERGENCY CARE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.652-653
  • Ankara Üniversitesi Adresli: Evet

Özet

Colchicine is an anti-inflammatory drug, which has been used for the treatment of familial Mediterranean fever for several decades with narrow therapeutic-toxicity window. Colchicine poisoning is rare but frequently a life-threatening emergency condition in pediatric practice. It may occur by excessive ingestion of colchicine tablets accidentally or intentionally. Herein, we report a suicide attempt with colchicine in a 12-year-old girl who had been followed up with the diagnosis of familial Mediterranean fever. She was admitted to our emergency department with gastrointestinal complaints and subsequently died because of the rapidly deteriorating metabolic and hemodynamic conditions.