Oral antidiabetic 2,4-thiazolidinedione derivative agents II 2,4-tiyazolidindion turevi oral antidiyabetik bilesikler II

Ertan R., Bozdag O.

Fabad Journal of Pharmaceutical Sciences, vol.25, no.2, pp.57-66, 2000 (Scopus) identifier

  • Publication Type: Article / Review
  • Volume: 25 Issue: 2
  • Publication Date: 2000
  • Journal Name: Fabad Journal of Pharmaceutical Sciences
  • Journal Indexes: Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.57-66
  • Keywords: 2,4-thiazolidinediones, Chemical reactions, Spectral data, Synthesis
  • Ankara University Affiliated: Yes

Abstract

In our previous paper, antidiabetic effects, structure-activity relationships and biotransformation of the 2,4-thiazolidindione (2,4-TZD) derivatives, which have been known to have various pharmacological properties, were reported. In this paper, chemical reactions such as cyclo- addition, nucleophilic addition, nucleophilic substitution and photochemical reactions, synthesis of the 2,4-TZD ring and other substituted derivatives, IR, NMR and Mass spectral data of the 2,4-TZD derivatives have been summarized.