A comparative study on the choroidal vascularity index and the determination of cut-off values in the pachychoroid spectrum diseases.

DEMİREL S., YANIK ODABAŞ Ö., Ozcan G., Batioglu F., ÖZMERT E.

Japanese journal of ophthalmology, cilt.65, sa.4, ss.482-491, 2021 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 65 Sayı: 4
  • Basım Tarihi: 2021
  • Doi Numarası: 10.1007/s10384-021-00829-5
  • Dergi Adı: Japanese journal of ophthalmology
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CAB Abstracts, EMBASE, MEDLINE, Veterinary Science Database
  • Sayfa Sayıları: ss.482-491
  • Anahtar Kelimeler: Choroidal vascularity index, Central serous chorioretinopathy, Pachychoroid neovasculopathy, Pachychoroid pigment epitheliopathy, Polypoidal choroidal vasculopathy
  • Ankara Üniversitesi Adresli: Evet

Özet

Purpose To determine the cut-off levels for choroidal thickness and choroidal vascularity index (CVI) to differentiate among pachychoroid spectrum diseases. Study design A retrospective comparative study Methods A total of 143 eyes were included. Of these 29 had uncomplicated pachychoroid (UCP), 29 had pachychoroid pigment epitheliopathy (PPE), 25 had pachychoroid neovasculopathy (PNV), 30 had central serous chorioretinopathy (CSC), and 30 had polypoidal choroidal vasculopathy (PCV). The choroidal areas were measured with ImageJ software. The CVI, the proportion of the luminal area to the total choroidal area, was assessed. Results The cut-off points of central choroidal thickness were determined as 360 mu m for the PPE and PCV group pair (p < 0.001), 422 mu m for the PNV and CSC group pair (p = 0.026), 271 mu m for the PNV and PCV group pair (p < 0.001), and 341 mu m for the CSC and PCV group pair (p < 0.001). The cut-off points of CVI were 72.7 for the PPE and PCV group pair (p < 0.001), 74.7 for the PNV and CSC group pair (p = 0.005), 72.6 for the PNV and PCV group pair (p = 0.001), and 73.6 for the CSC and PCV group pair (p < 0.001). Conclusion Pachychoroid spectrum may be composed of a combination of distinct choroidal diseases with different vascular and structural characteristics.