The Effects of 1,3,5-trisubstituted Indole Derivatives on Cell Growth, Apoptosis and MMP-2/9 mRNA Expression of MCF-7 Human Breast Cancer Cells

BAKAR ATEŞ F., KILIÇ KURT Z., ÇAĞLAYAN M. G., ÖLGEN S.

ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, cilt.17, sa.5, ss.762-767, 2017 (SCI-Expanded, Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 17 Sayı: 5
  • Basım Tarihi: 2017
  • Doi Numarası: 10.2174/1871520616666160802115737
  • Dergi Adı: ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.762-767
  • Anahtar Kelimeler: Indole, MMP-2, MMP-9, MCF-7, apoptosis, derivatives, breast cancer, NF-KAPPA-B, MATRIX METALLOPROTEINASES, TYROSINE KINASE, INHIBITORS, PROGRESSION, CADHERIN, THERAPY, PROTEIN
  • Ankara Üniversitesi Adresli: Evet

Özet

Background: Matrix metalloproteinases are known as extracellular matrix degrading enzymes and have important role on tumor progression.