Electroanalytical Investigation and Simultaneous Determination of Etodolac and Thiocolchicoside at a Non-Modified Glassy Carbon Electrode in Anionic Surfactant Media

Selcuk O., Erkmen C., BOZAL PALABIYIK B., USLU B.

ELECTROANALYSIS, cilt.33, sa.5, ss.1290-1298, 2021 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 33 Sayı: 5
  • Basım Tarihi: 2021
  • Doi Numarası: 10.1002/elan.202060623
  • Dergi Adı: ELECTROANALYSIS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, Aerospace Database, Applied Science & Technology Source, BIOSIS, Chemical Abstracts Core, Chimica, Communication Abstracts, Metadex, Civil Engineering Abstracts
  • Sayfa Sayıları: ss.1290-1298
  • Anahtar Kelimeler: Determination, etodolac, thiocolchicoside, voltammetry, anionic surfactant, PHARMACEUTICAL DOSAGE FORMS, HUMAN PLASMA, SQUARE-WAVE, HUMAN SERUM, NANOPARTICLES, OXIDATION, DRUG
  • Ankara Üniversitesi Adresli: Evet

Özet

In this study, a differential pulse voltammetry method was designed for the simultaneous determination of etodolac and thiocolchicoside in a tablet dosage form. This method is a sensitive, costless and reproducible one initially designed for the simultaneous determination of etodolac and thiocolchicoside using bare/unmodified glassy carbon electrode in the presence of sodium dodecyl sulfate. At optimized conditions, the method showed linear responses with etodolac and thiocolchicoside concentration in the range of 1 mu M to 80 mu M. The limits of detection and quantification were calculated as 0.11 mu M and 0.38 mu M for etodolac and 0.20 mu M and 0.67 mu M for thiocolchicoside, respectively.