Circulating CD44 and intercellular adhesion molecule-1 levels in low grade non-Hodgkin lymphoma and B-cell chronic lymphocytic leukemia patients during interferon-alpha-2a treatment

BEKSAÇ M., Arat M., Akan H., Koc H., Ilhan O., Ozcan M.

CANCER, vol.89, no.7, pp.1474-1481, 2000 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 89 Issue: 7
  • Publication Date: 2000
  • Journal Name: CANCER
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1474-1481
  • Keywords: soluble adhesion molecules, CD44, CD54, low grade non-Hodgkin lymphoma, chronic lymphocytic leukemia, SERUM LEVELS, PROGNOSTIC MARKERS, ICAM-1, EXPRESSION, CORRELATE, MALIGNANCIES, DISEASE, VARIANT, ALPHA
  • Ankara University Affiliated: Yes

Abstract

BACKGROUND. Despite published reports regarding the association of elevated circulating CD44 and CD54 levels with unfavorable outcome in non-Hodgkin lymphoma (NHL) and chronic lymphocytic leukemia (CLL), little is known about therapy-related changes in either adhesion molecule. In an attempt to evaluate the effect of interferon-alpha (IFN alpha), the authors measured serum CD44 (sCD44) and sCD54 in 22 low grade NHL and 14 CU. patients.