Circulating CD44 and intercellular adhesion molecule-1 levels in low grade non-Hodgkin lymphoma and B-cell chronic lymphocytic leukemia patients during interferon-alpha-2a treatment

BEKSAÇ M., Arat M., Akan H., Koc H., Ilhan O., Ozcan M.

CANCER, cilt.89, sa.7, ss.1474-1481, 2000 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 89 Sayı: 7
  • Basım Tarihi: 2000
  • Dergi Adı: CANCER
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1474-1481
  • Anahtar Kelimeler: soluble adhesion molecules, CD44, CD54, low grade non-Hodgkin lymphoma, chronic lymphocytic leukemia, SERUM LEVELS, PROGNOSTIC MARKERS, ICAM-1, EXPRESSION, CORRELATE, MALIGNANCIES, DISEASE, VARIANT, ALPHA
  • Ankara Üniversitesi Adresli: Evet

Özet

BACKGROUND. Despite published reports regarding the association of elevated circulating CD44 and CD54 levels with unfavorable outcome in non-Hodgkin lymphoma (NHL) and chronic lymphocytic leukemia (CLL), little is known about therapy-related changes in either adhesion molecule. In an attempt to evaluate the effect of interferon-alpha (IFN alpha), the authors measured serum CD44 (sCD44) and sCD54 in 22 low grade NHL and 14 CU. patients.