Cascade screening and treatment of children with familial hypercholesterolemia in Turkey

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KÖSE E., Kose M., Ozturk S. I., Ozcan E., Onay H., Ozkan B.

JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM, cilt.33, sa.10, ss.1251-1256, 2020 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 33 Sayı: 10
  • Basım Tarihi: 2020
  • Doi Numarası: 10.1515/jpem-2020-0234
  • Dergi Adı: JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, BIOSIS, CAB Abstracts, EMBASE, MEDLINE
  • Sayfa Sayıları: ss.1251-1256
  • Anahtar Kelimeler: children, familial hypercholesterolemia, low-fat diet, statin, CARDIOVASCULAR-DISEASE, COST-EFFECTIVENESS, FOLLOW-UP, ADOLESCENTS, EFFICACY, SAFETY, PRAVASTATIN, SERVICES, LIFE
  • Ankara Üniversitesi Adresli: Evet

Özet

Objectives: Premature coronary artery disease is the most common preventable cause of death in developed countries, and familial hypercholesterolemia (FH) is the most common monogenetic disorder of lipid metabolism, predisposing for premature coronary artery. FH is the most common preventable cause of death in developed countries. In 2016, the national lipid screening program in school-age children has been started in Turkey. In this study, we aimed to evaluate the efficacy of lipid screening program, lipid-lowering treatments, and the challenges of treatments in children diagnosed with FH.