Effect of dutasteride treatment on reducing blood loss and in perioperative period of open prostatectomy

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GÖKCE M. İ., Kerimov S., AKINCI A., Hamidi N., Afandiyev F., YAMAN M. Ö.

TURKISH JOURNAL OF UROLOGY, cilt.41, sa.1, ss.24-26, 2015 (ESCI) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 41 Sayı: 1
  • Basım Tarihi: 2015
  • Doi Numarası: 10.5152/tud.2015.90094
  • Dergi Adı: TURKISH JOURNAL OF UROLOGY
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, Academic Search Premier, CINAHL
  • Sayfa Sayıları: ss.24-26
  • Anahtar Kelimeler: Bleeding, benign prostatic hyperplasia, dutasteride, open prostatectomy, BENIGN PROSTATIC HYPERPLASIA, TRANSURETHRAL RESECTION, TRANSVESICAL PROSTATECTOMY, CONTEMPORARY SERIES, FOLLOW-UP, FINASTERIDE, PRETREATMENT, SYMPTOMS
  • Ankara Üniversitesi Adresli: Evet

Özet

Objective: Open prostatectomy (OP) is a valid option for the surgical treatment of large prostates in the absence of holmium laser enucleation. The most frequent complication of OP is intra-and perioperative bleeding. Preoperative use of dutasteride has been shown to reduce vascularity and perioperative bleeding in transurethral resection of the prostate (TUR-P). However, there has been no study addresing this effect in OP. The aim of this study was to evaluate whether pretreatment with dutasteride for 6 weeks before OP can reduce surgical blood loss.