Characteristics of "Early Type-I Pattern" (0-6 years) Hodgkin's disease in Turkish children

Çavdar A. O., Gözdaşoĝlu S., Yavuz G., ÜNAL E., Pamir A., TAÇYILDIZ N., ...Daha Fazla

Turkish Journal of Haematology, cilt.19, sa.1, ss.55-62, 2002 (SCI-Expanded) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 19 Sayı: 1
  • Basım Tarihi: 2002
  • Dergi Adı: Turkish Journal of Haematology
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.55-62
  • Anahtar Kelimeler: Turkish children, Type-I pattern Hodgkin's disease
  • Ankara Üniversitesi Adresli: Evet

Özet

The clinico-epidemiologic characteristics of 54 children with HD in 0-6 years of age group were retrospectively analyzed. This group represented 27% of 200 HD cases observed in our center and was named as early type-I pattern HD. The association of EBV with HD was also shown by serologic and immunohistochemical methods (LMP1) in these very young Turkish patients. T-cell immune deficiency, cytokine imbalance and Zn deficiency were additional findings found in these patients. This series seems to be the largest one studying early type-I HD, by several aspects.