Characteristics of "Early Type-I Pattern" (0-6 years) Hodgkin's disease in Turkish children
Turkish Journal of Haematology, cilt.19, sa.1, ss.55-62, 2002 (SCI-Expanded, Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 19 Sayı: 1
- Basım Tarihi: 2002
- Dergi Adı: Turkish Journal of Haematology
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.55-62
- Anahtar Kelimeler: Turkish children, Type-I pattern Hodgkin's disease
- Ankara Üniversitesi Adresli: Evet
Özet
The clinico-epidemiologic characteristics of 54 children with HD in 0-6 years of age group were retrospectively analyzed. This group represented 27% of 200 HD cases observed in our center and was named as early type-I pattern HD. The association of EBV with HD was also shown by serologic and immunohistochemical methods (LMP1) in these very young Turkish patients. T-cell immune deficiency, cytokine imbalance and Zn deficiency were additional findings found in these patients. This series seems to be the largest one studying early type-I HD, by several aspects.