Relationship between susceptibility to antimicrobials and virulence factors in paediatric Escherichia coli isolates

Arisoy M., Rad A. Y., Akin A., Akar N.

INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS, cilt.31, 2008 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 31
  • Basım Tarihi: 2008
  • Doi Numarası: 10.1016/j.ijantimicag.2007.07.030
  • Dergi Adı: INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Anahtar Kelimeler: Escherichia coli, antibiotics, susceptibility, virulence factor, URINARY-TRACT INFECTION, STRAINS, PREVALENCE
  • Ankara Üniversitesi Adresli: Evet

Özet

The in vitro susceptibilities to several antibiotics of 136 Escherichia coli strains containing virulence factors isolated from children with urinary tract infection were analysed. Escherichia coli strains were analysed by multiplex polymerase chain reaction for genes encoding the following virulence factors: pyelonephritis-associated pili (pap); S fimbriae (sfa); afimbrial adhesin I (afaI); haemolysin (hly); cytotoxic necrotizing factor I (cnfI); and aerobactin (aer). It was observed that the virulence genes increased antibiotic resistance of resistant strains and increased the sensitivity of susceptible strains. (c) 2007 Elsevier B.V. and the International Society of Chemotherapy. All rights reserved.