Comparison of cord blood pro-BNP levels in newborns of SARS-COV-2-positive and -negative women, and its association with adverse perinatal outcomes
International Journal of Gynecology and Obstetrics, cilt.161, sa.1, ss.308-313, 2023 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 161 Sayı: 1
- Basım Tarihi: 2023
- Doi Numarası: 10.1002/ijgo.14655
- Dergi Adı: International Journal of Gynecology and Obstetrics
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CAB Abstracts, CINAHL, EMBASE, Gender Studies Database, MEDLINE, Public Affairs Index
- Sayfa Sayıları: ss.308-313
- Anahtar Kelimeler: cord pro-BNP, maternal SARS-COV-2 positivity, NICU prediction, NATRIURETIC PEPTIDE LEVELS, DISEASE, RISK
- Ankara Üniversitesi Adresli: Evet
Özet
© 2023 International Federation of Gynecology and Obstetrics.Objective: To compare umbilical cord blood pro-B-type natriuretic peptide (BNP) levels in newborns of severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) positive pregnancies to those of SARS-COV-2 negative pregnancies. Methods: Prospectively cord blood samples from newborns of 42 SARS-COV-2 positive women, and 42 negative pregnant were collected at birth and analyzed for pro-BNP levels. Results: The mean cord blood pro-BNP level was significantly higher in newborns of SARS-COV-2 positive women than in controls. Furthermore, the pro-BNP level was an independent predictor of NİCU admission in both SARS-COV-2 positive and control patients. Conclusion: Cord blood pro-BNP level may be a parameter that can predict the under-stress fetus and adverse perinatal outcomes especially, in cases where placental involvement is present as in SARS-COV-2 infection.