Bioavailability file: Fluvoxamine Biyoyararlanim dosyasi: Fluvoksamin

Gönü N., Ertan R., BOZDAĞ DÜNDAR O.

Fabad Journal of Pharmaceutical Sciences, cilt.26, sa.1, ss.47-56, 2001 (Scopus) identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 26 Sayı: 1
  • Basım Tarihi: 2001
  • Dergi Adı: Fabad Journal of Pharmaceutical Sciences
  • Derginin Tarandığı İndeksler: Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.47-56
  • Anahtar Kelimeler: Antidepressant, Bioavailability, Fluvoxamine, Fluvoxamine maleate, Pharmacokinetics
  • Ankara Üniversitesi Adresli: Evet

Özet

Fluvoxamine, which specifically inhibits the serotonin reuptake, is an antidepressant compound from the series of 2-aminoethyloximethers of arylalkylketones, which is a newly developed and second generation antidepressant class. It is used in the treatment of psychiatric disorders such as depression, obsessive-compulsive and panic; aggression and posttraumatic stress disorders, bulimia and recently alcohol and drug abuse. In this article, the physicochemical properties, assay methods, pharmacological properties, pharmacokinetics and bioavailability of fluvoxamine and drug interactions are outlined.