Akademik Veri Yönetim Sistemi
Journal of Ear Nose Throat and Head Neck Surgery, cilt.32, sa.3, ss.118-127, 2024 (Scopus)
Objective: This study aims to evaluate efferent auditory system by medial olivocochlear (MOC) reflex on patients with multiple sclerosis (MS). Material and Methods: 53 participants with normal hearing (30 MS patients and 23 control group) was involved in the study. MS patients divided in two groups as “patients without definable brainstem lesion (Group 1, n=15)” and “patients with definable brainstem lesion (Group 2, n=15)” by cranial magnetic resonance imaging. All participants had pure tone audiometry, acoustic reflex test, transient evoked otoacoustic emission (TEOAE) amplitude measurements [with 80 ±4 dB peak equivalent sound pressure level (peSPL) click stimulus]. MOC pathway evaluated with contralateral suppresion measurement is made by 65 dB peSPL linear click stimulus with 50 dB SPL white noise on contralateral ear. Results: TEOAE signal to noise-ration (SNR) amplitudes on right ear on 2,000 and 2,800 Hz are found to be higher on control group than Group 2 (p<0.05). In the left ear, SNR amplitudes with 4,000 Hz in Group 1 and control group is higher than Group 2 (p<0.05). In terms of MOC reflex positivity ratio; there is no statistically meaningful difference (p>0.05). Mean suppresion in the control group’s left ears found to be higher than Group 2 left ears (p<0.05). Conclusion: Our results demonstrated TEOAE SNR amplitude reduction in MS patients with brainstem involvement. Even though no MOC reflex positivity ratio difference was found between groups, control groups suppression level on the left side found to be superior to Group 2. In MS patients, because of brainstem involvement; TEAOE SNR amplitudes and suppresion levels may decrease.