Significance of serum antibodies reactive with flavoprotein subunit of succinate dehydrogenase in thyroid associated orbitopathy

Hosal, MELEK; Swanson, JK; Thompson, CR; Kubota, S; Gunji, K; Kennerdell, JS; Wall, JR

doi:10.1136/bjo.83.5.605

Significance of serum antibodies reactive with flavoprotein subunit of succinate dehydrogenase in thyroid associated orbitopathy

Hosal B., Swanson J., Thompson C., Kubota S., Gunji K., Kennerdell J., ...Daha Fazla

BRITISH JOURNAL OF OPHTHALMOLOGY, cilt.83, sa.5, ss.605-608, 1999 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 83 Sayı: 5
Basım Tarihi: 1999
Doi Numarası: 10.1136/bjo.83.5.605
Dergi Adı: BRITISH JOURNAL OF OPHTHALMOLOGY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.605-608
Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
Ankara Üniversitesi Adresli: Hayır

Özet

Aims-Thyroid associated orbitopathy (TAO) is an autoimmune disorder of extraocular muscles and orbital connective tissue. Identification of the principal target antigens would help the understanding of the pathogenesis of the disease and possibly lead to the development of specific therapies in the future. The purpose of this study was to measure serum antibodies against the flavoprotein subunit of succinate dehydrogenase in patients with TAO and correlate their presence with factors of TAO.