Cisplatin causes oxidation in rat liver tissues: Possible protective effects of antioxidant food supplementation


Avci A., Cetin R., Erguder I. B., DEVRİM E., Kilicoglu B., Candir O., ...Daha Fazla

TURKISH JOURNAL OF MEDICAL SCIENCES, cilt.38, sa.2, ss.117-120, 2008 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 38 Sayı: 2
  • Basım Tarihi: 2008
  • Dergi Adı: TURKISH JOURNAL OF MEDICAL SCIENCES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.117-120
  • Anahtar Kelimeler: cisplatin, hepatotoxicity, antioxidant foods, protection, SUPEROXIDE-DISMUTASE ENZYMES, TOXICITY, LYCOPENE, OXIDASE, WINE, MICE
  • Ankara Üniversitesi Adresli: Evet

Özet

Aims: In this study, we aimed to investigate the possible molecular mechanism of cisplatin hepatotoxicity and to establish whether some natural antioxidant foods, namely dried black grape and tomato, may provide protection against cisplatin hepatotoxicity.