Turkish Neonatal Society position paper for stem cell therapy in neonates

Cetinkaya, Merih; KOÇ, ESİN; Acunas, Betul; AKISU, METE; ARSAN, SAADET; Canpolat, Fuat; Dilli, Dilek; Ince, Zeynep; KÖKSAL, FATMA; Kumral, Abdullah; Ozek, Eren; Ozkan, Hasan; Toygar, Ayse; Yigit, Sule; Zenciroglu, Aysegul; Vural, Mehmet

doi:10.1016/j.gpeds.2024.100239

Turkish Neonatal Society position paper for stem cell therapy in neonates

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Cetinkaya M., KOÇ E., Acunas B., AKISU M., ARSAN S., Canpolat F. E., ...More

Global Pediatrics, vol.11, 2025 (Scopus)

Publication Type: Article / Article
Volume: 11
Publication Date: 2025
Doi Number: 10.1016/j.gpeds.2024.100239
Journal Name: Global Pediatrics
Journal Indexes: Scopus
Keywords: Neonatal diseases, Neonatology, Position paper, Stem cell therapy
Ankara University Affiliated: Yes

Abstract

Stem cell (SC) therapy has been proposed as a promising therapeutic modality in neonatology, especially for prevention and/or treatment of several interactable diseases such as bronchopulmonary dysplasia, intraventricular hemorrhage, hypoxic-ischemic encephalopathy and others. However, there are several uncertainities in terms of indications, timing, dosage, and safety of SC therapy for routine clinical use in neonates. Herein, a group of Turkish Neonatal Society members evaluated the systematic reviews, meta-analyses, clinical and experimental studies and also case-reports in the literature about the usage of SC therapy in neonatal diseases.