Evaluation of hematologic indices in parvovirus infected dogs with systemic inflammatory response syndrome (SIRS)

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Sevim K., Çolakoğlu E. Ç., Kaya U.

TOPICS IN COMPANION ANIMAL MEDICINE, sa.66, ss.1-5, 2025 (SCI-Expanded)

• Yayın Türü: Makale / Tam Makale
• Basım Tarihi: 2025
• Doi Numarası: 10.1016/j.tcam.2025.100977
• Dergi Adı: TOPICS IN COMPANION ANIMAL MEDICINE
• Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Agricultural & Environmental Science Database, CAB Abstracts, MEDLINE, Veterinary Science Database
• Sayfa Sayıları: ss.1-5
• Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
• Ankara Üniversitesi Adresli: Evet

Özet

Canine parvoviral enteritis (CPE) is a highly contagious, acute viral disease that mainly affects young dogs and

can lead to systemic inflammatory response syndrome (SIRS), sepsis, endotoxemia and even death. The study

aimed to evaluate the diagnostic and prognostic potential of hematological indices such as MLR, NLR, PLR, PNR

and SII in CPV-infected dogs with SIRS at first admission. The retrospective study was performed on 51 CPVinfected and 20 healthy dogs. MLR, NLR, PLR, PNR, and SII indices were determined and compared between

groups. A receiver operating characteristic (ROC) curve analysis was carried out to determine thresholds of

sensitivity and specificity for hematologic indices.

NLR, PLR, and PNR were the best predictors for supporting a diagnosis of parvoviral enteritis, with AUC values

of 0.685, 0.762, and 0.884, respectively. Moreover, PLR and PNR, with AUC values of 0.740 and 0.769,

respectively, were the most suitable indices to determine the prognosis of dogs with parvoviral enteritis with

SIRS. In conclusion, these indices can be used as potential indicators for predicting disease outcomes and sup-

porting a diagnosis of CPV-infected dogs with SIRS at first admission.