Changes in isoprenaline-induced endothelium-dependent and -independent relaxations of aorta in long-term STZ-diabetic rats: Reversal effect of dietary vitamin E

Karasu C., Ozansoy G., Bozkurt O., Erdogan D., Omeroglu S.

GENERAL PHARMACOLOGY, vol.29, no.4, pp.561-567, 1997 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 29 Issue: 4
  • Publication Date: 1997
  • Doi Number: 10.1016/s0306-3623(96)00577-0
  • Journal Name: GENERAL PHARMACOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.561-567
  • Keywords: thoracic aorta, vitamin E, STZ-diabetes, endothelium, nitric oxide, isoprenaline, lipid peroxidation, electron microscopy, LIPOPROTEIN OXIDATION, ANTIOXIDANT TREATMENT, RESISTANCE ARTERIES, LIPID-PEROXIDATION, INSULIN-TREATMENT, THORACIC AORTA, NITRIC-OXIDE, RESPONSES, MELLITUS, ORGANIZATION
  • Ankara University Affiliated: No

Abstract

1. The present study concerns in vitro isoprenaline (ISO)-induced relaxation of aortic rings of long-term streptozotocin (STZ)-diabetic and nondiabetic rats, both with and without dietary vitamin E supplementation.