The role of PNPLA3 (rs738409) cg variant on histological progression of non-alcoholic fatty liver disease
Hepatology Forum, cilt.1, sa.3, ss.82-87, 2020 (ESCI, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 1 Sayı: 3
- Basım Tarihi: 2020
- Doi Numarası: 10.14744/hf.2020.2020.0023
- Dergi Adı: Hepatology Forum
- Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.82-87
- Anahtar Kelimeler: Genome-wide association studies (GWAS), nonalcoholic fatty liver disease, PNPLA3, steatohepatitis
- Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
- Ankara Üniversitesi Adresli: Evet
Özet
Background and Aim: The present study aims to investigate the role of genetic variability of the PNPLA3 gene (adiponectin) in predisposition to non-alcoholic fatty liver disease (NAFLD) by comparing NAFLD patients to healthy controls and to investigate any impact of the PNPLA3 genetic variability on the natural course of the disease.