The role of PNPLA3 (rs738409) cg variant on histological progression of non-alcoholic fatty liver disease

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İDİLMAN R., ÖZEN KARATAYLI S. C., KABAÇAM G., SAVAŞ B., ELHAN A. H., BOZDAYI A. M.

Hepatology Forum, vol.1, no.3, pp.82-87, 2020 (ESCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 1 Issue: 3
  • Publication Date: 2020
  • Doi Number: 10.14744/hf.2020.2020.0023
  • Journal Name: Hepatology Forum
  • Journal Indexes: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
  • Page Numbers: pp.82-87
  • Keywords: Genome-wide association studies (GWAS), nonalcoholic fatty liver disease, PNPLA3, steatohepatitis
  • Ankara University Affiliated: Yes

Abstract

Background and Aim: The present study aims to investigate the role of genetic variability of the PNPLA3 gene (adiponectin) in predisposition to non-alcoholic fatty liver disease (NAFLD) by comparing NAFLD patients to healthy controls and to investigate any impact of the PNPLA3 genetic variability on the natural course of the disease.