Adaptive control of S.cerevisiae production


Akay B., Ertunc S., Kahvecioglu A., Hapoglu H., Alpbaz M.

FOOD AND BIOPRODUCTS PROCESSING, cilt.80, sa.C1, ss.28-38, 2002 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 80 Sayı: C1
  • Basım Tarihi: 2002
  • Doi Numarası: 10.1205/096030802753479089
  • Dergi Adı: FOOD AND BIOPRODUCTS PROCESSING
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.28-38
  • Anahtar Kelimeler: linear adaptive PID control, non-linear adaptive PID control, baker's yeast production, INTEGRAL DERIVATIVE CONTROLLER, DISSOLVED-OXYGEN CONCENTRATION, TEMPERATURE CONTROL, BATCH
  • Ankara Üniversitesi Adresli: Evet

Özet

The growth medium temperature of a bioreactor, in which S.cerevisiae was produced at aerobic condition, was controlled applying adaptive PID technique. Glucose was used as an energy and carbon source in the growth medium, and an exothermic reaction took place as a result of the glucose consumption of the microorganism under aerobic condition. Then the specific growth rate of the microorganism was inhibited by the increasing growth medium temperature. To maintain the growth medium temperature at its set point which ensures maximum yeast productivity and quality in the bioreactor. non-linear adaptive PID and linear adaptive PID control systems were employed numerically. The bioreactor in which S. cerevisiae yeast was produced under the aerobic condition was considered as a batch system with respect to mass balance, The heat balance between the cooling jacket and the growth medium in the bioreactor was considered as a continuous system with respect to energy. These approximations were taken as a basis to develop the simulation work. In the Simulation studies, models for the bioprocess were developed by using mass and energy balance equations and solved by utilizing the Runge-Kutta-Felhberg method. The control algorithm developed was added to the simulated model.