Comparative study of laser flare photometry versus slit-lamp cell measurement in pediatric chronic non-infectious anterior uveitis
EUROPEAN JOURNAL OF OPHTHALMOLOGY, cilt.33, sa.1, ss.382-390, 2023 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 33 Sayı: 1
- Basım Tarihi: 2023
- Doi Numarası: 10.1177/11206721221107303
- Dergi Adı: EUROPEAN JOURNAL OF OPHTHALMOLOGY
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, CAB Abstracts, EMBASE, MEDLINE
- Sayfa Sayıları: ss.382-390
- Anahtar Kelimeler: uveitis (paediatric), PEDIATRIC OPHTHALMOLOGY, UVEA, anterior uveitis, complications of uveitis, anterior segment disease (includes cataract), JUVENILE IDIOPATHIC ARTHRITIS, COMPLICATIONS, MANAGEMENT
- Ankara Üniversitesi Adresli: Evet
Özet
Purpose To evaluate the role of laser flare photometry (LFP) for monitoring the course of intraocular inflammation in children with chronic anterior uveitis. Methods Seventy-six eyes of 43 children with non-infectious chronic anterior uveitis were reviewed retrospectively. Results The median follow-up was 48.6 +/- 23.1 months. Patients on immunosuppressive treatment at last follow-up, showed significantly higher flare values than patients who discontinued treatment (20.47 +/- 15.49 vs. 6.33 +/- 4.87 p < 0.001). The higher LFP values were correlated with the duration of immunosuppressive treatment, total duration of topical corticosteroid use and the risk for development of ocular complications at all follow-ups (all p < 0.001). No significant correlation was found between the AC cell grades and the duration of immunosuppressive treatment, topical corticosteroid use and the prevalence of complications. Conclusion LFP measurements have a predictive value of monitoring the course of uveitis and the occurrence of ocular complications, and it should be considered as a primary modality to monitor intraocular inflammation in children with chronic anterior uveitis.