Characterization of solid lipid nanoparticles (SLN™) and thei̇r pharmaceutical and cosmetic applications Kati li̇pi̇d nanoparti̇külleri̇n (SLN™) özelli̇kleri̇, farmasöti̇k ve kozmeti̇k alandaki̇ uygulamalari

BADILLI F. U., Tarimci N.

Ankara Universitesi Eczacilik Fakultesi Dergisi, cilt.35, sa.3, ss.211-235, 2006 (Scopus) identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 35 Sayı: 3
  • Basım Tarihi: 2006
  • Dergi Adı: Ankara Universitesi Eczacilik Fakultesi Dergisi
  • Derginin Tarandığı İndeksler: Scopus
  • Sayfa Sayıları: ss.211-235
  • Anahtar Kelimeler: Colloidal drug carrier system, High pressure homogenization, Lipid modifications (polymorphs), Solid lipid nanoparticles
  • Ankara Üniversitesi Adresli: Evet

Özet

Solid lipid nanoparticles (SLN) were introduced in 1991 and have gained increasing attention as an alternative drug carrier system to traditional colloidal carriers. In this review article, advantages - disadvantages and production procedures of SLNs are summarized. Also, methods of characterization of these colloidal carrier systems and the problems related to the production have been reviewed and the drug incorporation models taking place in the release of drug from SLNs have been described. And finally, in addition to the application methods of SLNs, examples of the studies on the pharmaceutic and cosmetic applications have been reviewed.