The prognostic significance of vascular endothelial growth factor levels in sera of non-small cell lung cancer patients.

Creative Commons License

Kaya A., Ciledag A., Gulbay B., Poyraz B., Çelik G., Sen E., ...More

Respiratory medicine, vol.98, no.7, pp.632-6, 2004 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 98 Issue: 7
  • Publication Date: 2004
  • Doi Number: 10.1016/j.rmed.2003.12.017
  • Journal Name: Respiratory medicine
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.632-6
  • Keywords: angiogenesis, vascular endothelial growth factor (VEGF), non-small cell lung cancer (NSCLC), enzyme-linked immunosorbent assay (ELISA), FACTOR VEGF, EXPRESSION, SURVIVAL, CARCINOMA
  • Ankara University Affiliated: Yes

Abstract

Background: Angiogenesis, the formation of new blood vessels from the existing vascular bed, is essential step for the growth and invasion of the primary tumor. Vascular endothelial growth factor (VEGF) is known to play crucial rote in tumor angiogenesis. Increased serum VEGF levels may be associated with poor prognosis in patients with non-small cell lung cancer (NSCLC).