High frequency of kidney and urinary tract anomalies in asymptomatic first-degree relatives of patients with CAKUT

BULUM AKBULUT B., ÖZÇAKAR Z. B., ÜSTÜNER E., DÜŞÜNCELİ ATMAN E., Kavaz A., DUMAN D., ...Daha Fazla

PEDIATRIC NEPHROLOGY, cilt.28, sa.11, ss.2143-2147, 2013 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 28 Sayı: 11
  • Basım Tarihi: 2013
  • Doi Numarası: 10.1007/s00467-013-2530-8
  • Dergi Adı: PEDIATRIC NEPHROLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.2143-2147
  • Anahtar Kelimeler: CAKUT, Familial clustering, First-degree relatives, Kidney and urinary tract anomalies, Renal ultrasound, CONGENITAL-ANOMALIES, RENAL ANOMALIES, MUTATIONS, CHILDREN, MALFORMATIONS, DUPLICATION, POPULATION, FAMILY, GENES, RET
  • Ankara Üniversitesi Adresli: Evet

Özet

Congenital anomalies of the kidney and urinary tract (CAKUT) commonly cause chronic kidney disease in children. While most CAKUT cases are sporadic, observed familial clustering suggests that the pathogenesis is influenced by genetic factors.