Comparison of Aqueous Flare Values after Micropulse Transscleral Laser Treatment and Continuous Wave Transscleral Cyclophotocoagulation

TEKELİ O., Kose H. C.

OCULAR IMMUNOLOGY AND INFLAMMATION, vol.31, no.3, pp.541-549, 2023 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 31 Issue: 3
  • Publication Date: 2023
  • Doi Number: 10.1080/09273948.2022.2042315
  • Journal Name: OCULAR IMMUNOLOGY AND INFLAMMATION
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CAB Abstracts, CINAHL, EMBASE, MEDLINE, Veterinary Science Database
  • Page Numbers: pp.541-549
  • Keywords: Aqueous flare, continuous wave, micropulse laser, transscleral diode cyclophotocoagulation, ANTERIOR-CHAMBER INFLAMMATION, SEMICONDUCTOR DIODE-LASER, RABBIT CILIARY BODY, GLAUCOMA, BARRIER, UVEITIS, PHOTOCOAGULATION, TRABECULECTOMY, PHOTOMETRY, OUTFLOW
  • Ankara University Affiliated: Yes

Abstract

Purpose The purpose of this study was to analyse the changes in flare values after Micropulse Transscleral Laser Treatment for Glaucoma (MP-TLT) in patients with refractory glaucoma and to compare with the outcomes of patients who underwent continuous wave (CW) diode laser cyclophotocoagulation (CW-TSCPC). Methods In this single-centre study, we reviewed the medical records of 54 patients who underwent MP-TLT and 35 patients who underwent CW-TSCPC at Ankara University Faculty of Medicine, Department of Ophthalmology. Aqueous flare values were measured by laser flare photometry. Results The mean laser flare values in both groups (MP-TLT/CW-TSCPC) increased after surgery from 20.85 +/- 8.74/22.14 +/- 7.39 ph/ms at baseline to 48.52 +/- 18.23/57.38 +/- 20.08 ph/ms (P = .001) on day 1 and then progressively decreased to 44.13 +/- 18.32/52.24 +/- 20.56 in week 1, 40.5 +/- 18.5/48.24 +/- 19.23 week 2 and 35.28 +/- 17.09/41.11 +/- 16.7 month 1 (all p < .05) and returned to similar levels to baseline at month 3 and month 6 (both p > .05). Patients who achieved treatment success had significantly higher flare values than patients who failed on post-operative day 1, week 1 and week 2 in both groups. The flare values were significantly lower in the MP-TLT group than the CW-TSCPC group on post-operative day 1, week 1, week 2 and month 1 (all p < .05). There were no cases of prolonged post-operative inflammation or serious complications in both groups. Conclusion Intraocular inflammation, quantified by aqueous flare, may be a contributing factor to the IOP lowering effect of transscleral diode laser cyclophotocoagulation in the early post-operative period.