Implantation of novel small-diameter polyurethane vascular prostheses interposed in canine femoral and carotid arteries


Karapinar K., Ulus A., Tutun U., Aksoyek A., APAYDIN N., Pamuk K., ...Daha Fazla

EUROPEAN SURGICAL RESEARCH, cilt.36, sa.4, ss.241-248, 2004 (SCI-Expanded, Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 36 Sayı: 4
  • Basım Tarihi: 2004
  • Doi Numarası: 10.1159/000078859
  • Dergi Adı: EUROPEAN SURGICAL RESEARCH
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.241-248
  • Anahtar Kelimeler: polyurethane, vascular prostheses, patency, canine arteries, GRAFTS, ENDOTHELIALIZATION, VEIN, PERFORMANCE
  • Ankara Üniversitesi Adresli: Hayır

Özet

Objectives: The performance of small-diameter (3-5 mm) vascular grafts still poses a challenge in the field of vascular surgery. We present here our preliminary experience with implanting unique small-sized polycarbonate urethane vascular grafts in 7 dogs. Material and Methods: Each animal was implanted with 4 interposition grafts, 2 femoral and 2 carotid. No anti-thrombotic medication was administered. Doppler sonography was performed at 3-month intervals to examine for patency and flow characteristics. Animals were sacrificed electively at 3, 6 and 12 months. Results: At 3 months, all grafts were patent. After 6 months, 3 grafts occluded and at 1 year a further 6 grafts occluded. Hence 9 of 28 grafts occluded (67.9% patency). During the study, no correlation could be established between flow velocity or resistance index and occlusion. Histopathology showed intimal hyperplasia to be the cause of occlusion. Conclusions: Compared to literature data on small-diameter grafts in the same position, ADIAM's Biomechanical grafts performed clearly better. Compliance data suggest a correlation between elastic compliance and patency. Copyright (C) 2004 S. Karger AG, Basel.