Implantation of novel small-diameter polyurethane vascular prostheses interposed in canine femoral and carotid arteries
EUROPEAN SURGICAL RESEARCH, vol.36, no.4, pp.241-248, 2004 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 36 Issue: 4
- Publication Date: 2004
- Doi Number: 10.1159/000078859
- Journal Name: EUROPEAN SURGICAL RESEARCH
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.241-248
- Keywords: polyurethane, vascular prostheses, patency, canine arteries, GRAFTS, ENDOTHELIALIZATION, VEIN, PERFORMANCE
- Ankara University Affiliated: No
Abstract
Objectives: The performance of small-diameter (3-5 mm) vascular grafts still poses a challenge in the field of vascular surgery. We present here our preliminary experience with implanting unique small-sized polycarbonate urethane vascular grafts in 7 dogs. Material and Methods: Each animal was implanted with 4 interposition grafts, 2 femoral and 2 carotid. No anti-thrombotic medication was administered. Doppler sonography was performed at 3-month intervals to examine for patency and flow characteristics. Animals were sacrificed electively at 3, 6 and 12 months. Results: At 3 months, all grafts were patent. After 6 months, 3 grafts occluded and at 1 year a further 6 grafts occluded. Hence 9 of 28 grafts occluded (67.9% patency). During the study, no correlation could be established between flow velocity or resistance index and occlusion. Histopathology showed intimal hyperplasia to be the cause of occlusion. Conclusions: Compared to literature data on small-diameter grafts in the same position, ADIAM's Biomechanical grafts performed clearly better. Compliance data suggest a correlation between elastic compliance and patency. Copyright (C) 2004 S. Karger AG, Basel.