Hashimoto Encephalopathy Causing Drug-Resistant Status Epilepticus Treated With Plasmapheresis

BEKTAŞ Ö., Yilmaz A., KENDİRLİ T., ŞIKLAR Z., Deda G.

PEDIATRIC NEUROLOGY, vol.46, no.2, pp.132-135, 2012 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 46 Issue: 2
  • Publication Date: 2012
  • Doi Number: 10.1016/j.pediatrneurol.2011.11.009
  • Journal Name: PEDIATRIC NEUROLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.132-135
  • Ankara University Affiliated: Yes

Abstract

Hashimoto encephalopathy is a rare, clinically heterogenous condition. Its treatment is based on corticosteroids. A previously normal 12-year-old boy was admitted to our pediatric emergency department with status epilepticus. He experienced a recurrence of status epilepticus after pentobarbital withdrawal, and required repeated resumptions of drug-induced coma. He manifested acute personality changes. His limbic encephalitis markers were normal, but his level of anti-thyroid peroxidase antibody was high. A diagnosis of Hashimoto encephalopathy was considered. Our patient responded to plasmapheresis instead of corticosteroid treatment. This case report is the first, to the best of our knowledge, of plasmapheresis because of Hashimoto encephalopathy in a child. Crown Copyright (C) 2012 Published by Elsevier Inc. All rights reserved.