Akademik Veri Yönetim Sistemi
Ankara Universitesi Eczacilik Fakultesi Dergisi, cilt.48, sa.1, ss.215-225, 2024 (Scopus)
Objective: The public's considerstion of natural resources as safe and the tendency not to use synthetic component-containing products have increased the use of essential oils recently. However, since essential oils contain a vast number of compounds, there are difficulties in standardization. For this reason, monographs are used to evaluate the quality of the essential oils and their use for therapeutic purposes. As a result of various studies, it has been shown that nioli essential oil can be used against upper respiratory tract and urinary tract infections and skin disorders and has antioxidant, anti-inflammatory, antiseptic, antifungal, antibacterial, anthelmintic, insecticidal, larvicidal and acaricidal activities. It is traditionally used against cold, influenza, cough, sinusitis, pharyngitis, rhinitis, rheumatic disorders and urinary system infections. Due to these activities and its traditional use; it is aimed to evaluate the compliance of some nioli essential oil samples available on the market with the Turkish Pharmacopoeia 2017. Material and Method: In the content of this study; nioli essential oil samples of 5 different brands are analyzed according to the monograph given in Turkish Pharmacopoeia (2017). In the analysis; relative density, refractive index, optical rotation values were determined; organoleptic control, thin layer chromatography and gas chromatography analyzes were carried out. Result and Discussion: As the result of the pharmacopoeia analysis conducted within the scope of the study, only one of the five nioli essential oil samples provided was found to comply with the pharmacopoeia standard. Other nioli essential oil samples did not meet the required conditions in the pharmacopoeia.