Cases of glioblastoma multiforme metastasizing to spinal cord

Karaca M., Andrieu M. N., Hicsonmez A., Guney Y., Kurtman C.

NEUROLOGY INDIA, vol.54, no.4, pp.428-430, 2006 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 54 Issue: 4
  • Publication Date: 2006
  • Doi Number: 10.4103/0028-3886.28122
  • Journal Name: NEUROLOGY INDIA
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.428-430
  • Keywords: glioblastoma multiforme, intramedullary metastasis, leptomeningeal dissemination, radiotherapy, CEREBROSPINAL-FLUID, MALIGNANT GLIOMAS, DISSEMINATION, DIAGNOSIS, CHILDREN
  • Ankara University Affiliated: Yes

Abstract

Cases of glioblastoma multiforme (GBM) metastasizing to the leptomeninx or the intramedullary spine are quite rare and prognoses are relatively poor. We present three cases of GBM with spinal metastasis, one of which also had leptomeningeal dissemination. Three patients with GBM were admitted to our clinic for postoperative radiotherapy after surgery. Leptomeningeal metastasis and dissemination were diagnosed with magnetic resonance imaging. Radiotherapy provided only temporary relief from pain with small improvement in neurological deficit but no survival advantage.