Blood HbA1C levels in dogs with diabetes mellitus Diyabetli köpeklerde kan HbA1C düzeyleri


Taşçene N., Karagül H.

Ankara Universitesi Veteriner Fakultesi Dergisi, vol.55, no.2, pp.75-78, 2008 (SCI-Expanded) identifier

  • Publication Type: Article / Article
  • Volume: 55 Issue: 2
  • Publication Date: 2008
  • Journal Name: Ankara Universitesi Veteriner Fakultesi Dergisi
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.75-78
  • Keywords: Diabetes mellitus, Dog, Glycosylated haemoglobin, HbA1c
  • Ankara University Affiliated: Yes

Abstract

The phenomenon of glucose molecules binding to proteins by a nonenzymatic glycation mechanism are known as glycated hemoglobin which is directly related to the amount of blood glucose levels. The level of HbA1c are increased in hyperglicaemia. Glycated Hb is an index of the mean blood glucose concentration over the long period. This index is not effected from the glycemic fluctuations in a short period. Therefore, HbA1c can be a good sign for controlling the blood sugar in Diabetes mellitus. In veterinary medicine, hyperglicaemia can be seen in the stress conditions during the blood sample collection from cats and dogs. HbA1c level is not effected from hyperglycemia in stress conditions. In this study, blood glucose and HbA 1c levels were analysed and compared with the control group levels for the evolutions of blood HbA1c levels in dogs with Diabetes mellitus. The blood serum glucose levels in dogs with Diabetes mellitus and the control dogs were found to be 526.71±22 mg/dl and 97.80±2.93 mg/dl respectively. Moreover blood HbA1c levels of diabetic and control dogs were found 3.11±0.4 % and 1.07±0.08 % respectively. The blood HbA1c levels in Diabetes mellitus group in comparison to control group were found to be statisticaly higher (p<0.01).