Detection of sasX Gene and Distribution of SCCmec Types in Invasive and Non-invasive Coagulase-negative Staphylococci

TEKELİ F. A., ÖCAL D., Dolapci I.

BALKAN MEDICAL JOURNAL, cilt.37, sa.4, ss.215-221, 2020 (SCI-Expanded) identifier identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 37 Sayı: 4
  • Basım Tarihi: 2020
  • Doi Numarası: 10.4274/balkanmedj.galenos.2020.2019.8.21
  • Dergi Adı: BALKAN MEDICAL JOURNAL
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CAB Abstracts, CINAHL, EMBASE, MEDLINE, Veterinary Science Database, Directory of Open Access Journals, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.215-221
  • Anahtar Kelimeler: Antimicrobial resistance, coagulase-negative staphylococci, molecular epidemiology, sasX, SCCmec, EPIDERMIDIS, IDENTIFICATION, MEC, AUREUS, STRAINS, CLONES
  • Ankara Üniversitesi Adresli: Evet

Özet

Background: Coagulase-negative staphylococci, which belong to the normal microbiota of the skin and mucous membranes, are opportunistic pathogens. sasX, a newly described protein, is thought to play an important role in nasal colonization and methicillin-resistant Staphylococcus aureus virulence, and it may be acquired from coagulase-negative staphylococci by horizontal gene transfer. It has been considered that understanding the function of sasX gene may help clarify the relevance of the different adhesion mechanisms in the pathogenesis of infections associated with biofilm.