Research Information System
Ankara Universitesi Eczacilik Fakultesi Dergisi, vol.49, no.1, pp.211-227, 2025 (Scopus)
Objective: Fragrance components are often included in perfumes, household cleaning products, personal care and cosmetic products today. There are some studies that showed these components led to phototoxicity and photoallergy as a result of sunlight exposure. For this reason, the safety assessment of fragrance components is of great importance. The safety evaluation of the fragrance components is carried out by various tests and methods, they are examined by the relevant organizations. In this review, the risk assessment processes of fragrance components, phototoxicity (photoiritation) and photoallergy reactions, mechanisms caused by sunlight exposure and test methods used to evaluate these negative reactions are summarized. In addition, the safety evaluations of the fragrance components most commonly used in formulations were examined, and the results in terms of phototoxicity and photoallergenicity were also mentioned. Result and Discussion: The preliminary identification of the components that cause phototoxicity and photoallergy reactions is very important in the production processes and product development stages. Also, having information about these types of components allows consumers to make informed product choices to protect skin health.