Alfuzosin attenuates erectile dysfunction in rats with partial bladder outlet obstruction

GÜR, SERAP; Sikka, Suresh; Chandra, Surabhi; Koka, Padma; Agrawal, Krishna; Kadowitz, Philip; Hellstrom, Wayne

doi:10.1111/j.1464-410x.2008.07914.x

Alfuzosin attenuates erectile dysfunction in rats with partial bladder outlet obstruction

GÜR S., Sikka S. C., Chandra S., Koka P. S., Agrawal K. C., Kadowitz P. J., ...Daha Fazla

BJU INTERNATIONAL, cilt.102, sa.11, ss.1651-1657, 2008 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 102 Sayı: 11
Basım Tarihi: 2008
Doi Numarası: 10.1111/j.1464-410x.2008.07914.x
Dergi Adı: BJU INTERNATIONAL
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.1651-1657
Anahtar Kelimeler: rat model, partial bladder outlet obstruction, nitric oxide synthase, alfuzosin, erectile function, BENIGN PROSTATIC HYPERPLASIA, CAVERNOSUM SMOOTH-MUSCLE, URINARY-TRACT SYMPTOMS, NITRIC-OXIDE SYNTHASE, CORPUS CAVERNOSUM, COMBINATION THERAPY, SEXUAL DYSFUNCTION, RHO-KINASE, L-ARGININE, IN-VITRO
Ankara Üniversitesi Adresli: Evet

Özet

To determine how partial bladder outlet obstruction (PBOO) in a rat model affects erectile function, and whether an uroselective alpha 1-adrenoceptor antagonist, alfuzosin (Sanofi-Aventis, Paris, France) attenuates any erectile dysfunction (ED).