Alfuzosin attenuates erectile dysfunction in rats with partial bladder outlet obstruction

GÜR S., Sikka S. C., Chandra S., Koka P. S., Agrawal K. C., Kadowitz P. J., ...Daha Fazla

BJU INTERNATIONAL, cilt.102, sa.11, ss.1651-1657, 2008 (SCI-Expanded, Scopus) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 102 Sayı: 11
  • Basım Tarihi: 2008
  • Doi Numarası: 10.1111/j.1464-410x.2008.07914.x
  • Dergi Adı: BJU INTERNATIONAL
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1651-1657
  • Anahtar Kelimeler: rat model, partial bladder outlet obstruction, nitric oxide synthase, alfuzosin, erectile function, BENIGN PROSTATIC HYPERPLASIA, CAVERNOSUM SMOOTH-MUSCLE, URINARY-TRACT SYMPTOMS, NITRIC-OXIDE SYNTHASE, CORPUS CAVERNOSUM, COMBINATION THERAPY, SEXUAL DYSFUNCTION, RHO-KINASE, L-ARGININE, IN-VITRO
  • Ankara Üniversitesi Adresli: Evet

Özet

To determine how partial bladder outlet obstruction (PBOO) in a rat model affects erectile function, and whether an uroselective alpha 1-adrenoceptor antagonist, alfuzosin (Sanofi-Aventis, Paris, France) attenuates any erectile dysfunction (ED).