Ginger (Zingiber officinale Roscoe) for the treatment and prevention of necrotizing enterocolitis

Cakir U., Tayman C., Serkant U., Yakut H. I., Cakir E., ATEŞ U., ...Daha Fazla

JOURNAL OF ETHNOPHARMACOLOGY, cilt.225, ss.297-308, 2018 (SCI-Expanded, Scopus) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 225
  • Basım Tarihi: 2018
  • Doi Numarası: 10.1016/j.jep.2018.07.009
  • Dergi Adı: JOURNAL OF ETHNOPHARMACOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.297-308
  • Anahtar Kelimeler: Necrotizing enterocolitis, Ginger, anti-oxidation, Anti-inflammation, Prevention, Newborn, Rat, TONGLING WHITE GINGER, NEONATAL-RAT MODEL, INTESTINAL BARRIER, ULCERATIVE-COLITIS, LIPID-PEROXIDATION, OXIDATIVE STRESS, ESSENTIAL OIL, PC12 CELLS, IN-VITRO, ANTIOXIDANT
  • Ankara Üniversitesi Adresli: Hayır

Özet

Ethnopharmacological relevance: Necrotizing enterocolitis (NEC) is the most important gastrointestinal emergency affecting especially preterm infants and causes severe morbidities and mortality. However, there is no cure. Oxidant stress, inflammation, apoptosis, as well as prematurity are believed to responsible in the pathogenesis of the disease. Ginger and its compounds have anti-inflammatory, antimicrobial, anti-oxidant properties and immunomodulatory, cytoprotective/regenerative actions.