A TALE OF CAPTOPRIL DETECTION BASED ON AN ELECTROCHEMICAL MIP SENSOR
Ankara Üniversitesi Eczacılık Fakültesi Dergisi, cilt.48, sa.2, ss.568-575, 2024 (Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 48 Sayı: 2
- Basım Tarihi: 2024
- Doi Numarası: 10.33483/jfpau.1420660
- Dergi Adı: Ankara Üniversitesi Eczacılık Fakültesi Dergisi
- Derginin Tarandığı İndeksler: Scopus, Central & Eastern European Academic Source (CEEAS), EMBASE, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.568-575
- Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
- Ankara Üniversitesi Adresli: Evet
Özet
Objective: In this study, it was aimed to develop a voltammetric method using sensors prepared with the molecular imprinting technique for the detection of Captopril, an antihypertensive drug. Material and Method: With the molecular imprinting method, molecularly imprinted polymers were formed on the surfaces of glassy carbon electrodes. The analysis of Captopril was carried out using the differential pulse voltammetry method, and the performance of the sensor was examined. Result and Discussion: A linear analysis was performed up to 50 pM Captopril with a limit of detection value of 2.62 pM. Selectivity studies have shown that Captopril has a higher electrochemical response than other interfering substances, such as paracetamol, ascorbic acid, and L-proline.